Structure of PDB 4v71 Chain BO Binding Site BS02

Receptor Information

>4v71 Chain BO (length=116) Species: 83333 (Escherichia coli K-12)

DKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAA
STVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHG
RVQALADAAREAGLQF

Ligand information

>4v71 Chain BB (length=117)

gccuggcggccguagcgcgguggucccaccugaccccaugccgaacucag
aagugaaacgccguagcgccgaugguaguguggggucuccccaugcgaga
guagggaacugccaggc

<<<<<<<<......<<<<<<<<....<<<<<<<.............>>>>
..>>>...>>>>>>.>>.<<.......<<<<<<<<...>>>>>>>>....
...>>....>>>>>>>>

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4v71 Energy barriers and driving forces in tRNA translocation through the ribosome.
• Resolution: 20.0 Å
• Binding residue (original residue number in PDB): K3 R10 R15 H29 R30 T31 R33 H34 Y36 Q38 I40 G44 V54 E55 K56 Y64 Q98 H100 R102
• Binding residue (residue number reindexed from 1): K2 R9 R14 H28 R29 T30 R32 H33 Y35 Q37 I39 G43 V53 E54 K55 Y63 Q97 H99 R101

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4v71, PDBe:4v71, PDBj:4v71
• PDBsum: 4v71
• PubMed: 24186064
• UniProt: P0C018|RL18_ECOLI Large ribosomal subunit protein uL18 (Gene Name=rplR)