Structure of PDB 4v6u Chain BO Binding Site BS02

Receptor Information
>4v6u Chain BO (length=197) Species: 186497 (Pyrococcus furiosus DSM 3638) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAHGPRYRVPFRRRREGKTNYRKRLKLLKSGKPRLVVRKSLNHHIAQIIV
YDPKGDRTLVSAHTRELIRDFGWKGHCGNTPSAYLLGLLIGYKAKQAGIE
EAILDIGLHPPVRGSSVFAVLKGAVDAGLNVPHSPEIFPDEYRIRGEHIA
EYAKMLKEQDEEKFRRQFGGYLVKGLDPEKLPEHFEEVKARIIEKFE
Ligand information
>4v6u Chain B3 (length=126) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cggcggccauagcgggggggccacacccggucucauuucgaacccggaag
uuaagccccccagcgaucccgguuguacugcccuccgagagggggcggga
agccggggacgccgccggccacuauc
.<<<<<<....<<<<<<<<.....<<<<<<.............>>>>..>
>....>>>>>>.>>..<<<<<<<....<<<<<<.<<....>>>>>>>>..
.>>>>>>>..>>>>>>..........
Receptor-Ligand Complex Structure
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PDB4v6u Promiscuous behaviour of archaeal ribosomal proteins: Implications for eukaryotic ribosome evolution.
Resolution6.6 Å
Binding residue
(original residue number in PDB)
M1 H3 G4 V9 F11 R12 R13 R15 K18 Y21 R24 R38 S40 L41 N42 H43 Q47 I49 P53 K54 G55 D56 T58 S61 E66 R69 H76 N79 T80 H109 P110 R113 G114 S116 R143 H148 I149 Y152 F168 L172 V173 K174
Binding residue
(residue number reindexed from 1)
M1 H3 G4 V9 F11 R12 R13 R15 K18 Y21 R24 R38 S40 L41 N42 H43 Q47 I49 P53 K54 G55 D56 T58 S61 E66 R69 H76 N79 T80 H109 P110 R113 G114 S116 R143 H148 I149 Y152 F168 L172 V173 K174
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:4v6u, PDBe:4v6u, PDBj:4v6u
PDBsum4v6u
PubMed23222135
UniProtQ9HH80|RL18_PYRFU Large ribosomal subunit protein uL18 (Gene Name=rpl18)

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