Structure of PDB 8oeq Chain BM Binding Site BS02

Receptor Information
>8oeq Chain BM (length=179) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANLRTQKRLAASVIGVGKRKVWLDPNETTEIANANSRSAIRKLYKNGTIV
KKPETVHSRSRARALKESKRAGRHMGYGKRKGTKDARMPSQVLWMRRLRV
LRKLLAKYRDAGKIDKHLYHNLYKAAKGNTFKHKRSLVEHIIAAKAEALR
EKALKEEAEARRVRNRAARERRQQRLAEK
Ligand information
>8oeq Chain CM (length=1726) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguauacuuggauaaccgugguaau
ucuagagcuaauacaugcuuaaaaucccgacuguuuggaagggauguauu
uauuagauaaaaaaucaaugccuucgggcucuuugaugauucauaauaac
uuuucgaaucgcauggccuugugcuggcgaugguucauucaaauuucugc
ccuaucaacuuucgaugguaggauaguggccuaccaugguuucaacgggu
aacggggaauaaggguucgauuccggagagggagccugagaaacggcuac
cacauccaaggaaggcagcaggcgcgcaaauuacccaaucccgacacggg
gagguagugacaauaaauaacgauacaggguuguaauuggaaugaguaca
auguaaauaccuuaacgaggaacaauuggagggcaagucuggugccagca
gccgcgguaauuccagcuccaaaagcguauauuaaaguuguugcaguuaa
aaagcucguaguugaaccuugggcuuggcuggccgguccuggacccagcc
gagccuuuccuucuggguagccauuuauggcgaaccaggacuuuuacuuu
gaaaaaauuagaguguucaaagcaggccuuugcucgaauauauuagcaug
gaauaauagaauaggacguuaugguucuauuuuguugguuucuaggacca
ucguaaugauuaauagggacggucggggguaucaguauucaguugucaga
ggugaaauucuuggauuuacugaagacuaacuacugcgaaagcauuuacc
aaggacguuuucauuaaucaagaacgaaaguuaggggaucgaagaugauc
agauaccgucguagucuuaaccauaaacuaugccgacuagggaucgguug
uuguucuuuuauugacgcaaucggcaccuuacgagaaaucaaagucuuug
gguucuggggggaguauggucgcaaggcugaaacuuaaaggaauugacgg
aagggcaccaccaggaguggagccugcggcuuaauuugacucaacacggg
gaaacucaccagguccagacacaauaaggauugacagauugagagcucuu
ucuugauuuugugggugguggugcauggccguucuuaguugguggaguga
uuugucugcuuaauugcgauaacgaacgagaccuuaaccuacuaaauagu
gcugcuagcauuugcugguauagucacuucuuagagggacuaucgauuuc
aagucgauggaaguuugaggcaauaacaggucugugaugcccuuagacgu
ucugggccgcacgcgcgcuacacugacggagccagcgaguagccuuggcc
gagaggucugggaaaucuugugaaacuccgucgugcuggggauagagcau
uguaauuguugcucuucaacgaggaauuccuaguaagcgcaagucaucag
cuugcguugauuacgucccugcccuuuguacacaccgcccgucgcuacua
ccgauugaauggcuuagugaggccuccggauugguuuagggaaccgagaa
gcuggucaaacuuggucauuuagaggaaguaaaagucguaacaagguuuc
cguaggugaaccugcggaaggaucau
...<<<<<.{.((((>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<.........<<.....<..<<.....
..>>..>......>>........<<<<<..<<....>>..>>>>><...<
<<<<<.........((((.<<<....>>>..............>>>>>>.
....>...<<<<..<<<.....>>>.>>>>....>>>...>>>>..>>>.
<<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>.
..<<<.<<<<....>>>>....>>>.>>.<<.<<<..........>>>.>
>.<.<<....>>.>...>>>>>>.........<<<....<<<<...>>>>
..>>>..>....>.>.....<<<<...<...>...>>>>......<<..<
...........>..>>.........<<<<<((......<<<<.....<<.
.))>>.......>>>>.>>>>>..>>>>>>>>>>.........<<<[[..
...<.<<...<<<.<<....<<<<<<<<<<<<............>>>>>>
>>>>>>......<<......................>>.....<<<<<.<
<.......<<...<.......>..<<<....>>>....>>......>>.>
>..>>>.........<<<..<<<<<<<<<.....))))....>>>>>>>>
>>>>.....>>....<<<<<<.<<...<<<<..<<..<<<<<<.<...<<
<......>>>......>.>>>>>>..>>.......<<....>>...>>>>
...>>>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.<.
....>.>>>>...>>>>>>>>..........<<<.<<.<<<..<<<<<<<
<..<<........>>.>>>>>>>>..>>>...<<..]]>>...>>.....
>>>.>>>.<<<......<<<<....>>>>....>>>..)))).}<<<<<.
<<<<<<<..<<.<<<<<<..<<<.<<<<<<......<<........>>..
........<<<<<.<....<<<<<........<<.<<<........>>>.
>>......>>>>>...<<.<<<..<<.<<<<<.....<<<.<<<<<....
>>>...<<<......>>>...>>.>>>....<<<<<.<<..<<<<..<<<
<.<<<<<<<....>>>>>>>....>>>>..>>>>.>>....<<<<<<...
..>>>>>>.......>>>>>.....>>.>>>.....>>>>>>>.....>.
>>>>>...>>.>>>>.>>>.....<<<<<<<......<<...<<<.<<<<
....>>>>.>>>....>>.......>>>>>>>...........<<<<<<.
.........>>>>>>..........>>>>>>....<<<<<<<<.......
>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.
<<....<<<<<<<<.<<<..<<<<..<...<<<<<.......>>>>>...
>..>>>>..>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<
<<<<<<<..>>>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8oeq Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution3.3 Å
Binding residue
(original residue number in PDB)
R162 R163 R165 N166 R170 R172 R173 R176
Binding residue
(residue number reindexed from 1)
R161 R162 R164 N165 R169 R171 R172 R175
External links
PDB RCSB:8oeq, PDBe:8oeq, PDBj:8oeq
PDBsum8oeq
PubMed
UniProtA0A1D8PK40|RL19A_CANAL Large ribosomal subunit protein eL19 (Gene Name=RPL19A)

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