Structure of PDB 8cre Chain BM Binding Site BS02

Receptor Information
>8cre Chain BM (length=179) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANLRTQKRLAASVIGVGKRKVWLDPNETTEIANANSRSAIRKLYKNGTIV
KKPETVHSRSRARALKESKRAGRHMGYGKRKGTKDARMPSQVLWMRRLRV
LRKLLAKYRDAGKIDKHLYHNLYKAAKGNTFKHKRSLVEHIIAAKAEALR
EKALKEEAEARRVRNRAARERRQQRLAEK
Ligand information
>8cre Chain CM (length=1765) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguaccuuacuacuuggauaaccgu
gguaauucuagagcuaauacaugcuuaaaaucccgacuguuuggaaggga
uguauuuauuagauaaaaaaucaaugccuucgggcucuuugaugauucau
aauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaau
uucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuca
acggguaacggggaauaaggguucgauuccggagagggagccugagaaac
ggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaaucccga
cacggggagguagugacaauaaauaacgauacagggcccuuuugggucuu
guaauuggaaugaguacaauguaaauaccuuaacgaggaacaauuggagg
gcaagucuggugccagcagccgcgguaauuccagcuccaaaagcguauau
uaaaguuguugcaguuaaaaagcucguaguugaaccuugggcuuggcugg
ccgguccauaugcguacuggacccagccgagccuuuccuucuggguagcc
auuuauggcgaaccaggacuuuuacuuugaaaaaauuagaguguucaaag
caggccuuugcucgaauauauuagcauggaauaauagaauaggacguuau
gguucuauuuuguugguuucuaggaccaucguaaugauuaauagggacgg
ucggggguaucaguauucaguugucagaggugaaauucuuggauuuacug
aagacuaacuacugcgaaagcauuuaccaaggacguuuucauuaaucaag
aacgaaaguuaggggaucgaagaugaucagauaccgucguagucuuaacc
auaaacuaugccgacuagggaucgguuguuguucuuuuauugacgcaauc
ggcaccuuacgagaaaucaaagucuuuggguucuggggggaguauggucg
caaggcugaaacuuaaaggaauugacggaagggcaccaccaggaguggag
ccugcggcuuaauuugacucaacacggggaaacucaccagguccagacac
aauaaggauugacagauugagagcucuuucuugauuuugugggugguggu
gcauggccguucuuaguugguggagugauuugucugcuuaauugcgauaa
cgaacgagaccuuaaccuacuaaauagugcugcuagcauuugcugguaua
gucacuucuuagagggacuaucgauuucaagucgauggaaguuugaggca
auaacaggucugugaugcccuuagacguucugggccgcacgcgcgcuaca
cugacggagccagcgaguauaagccuuggccgagaggucugggaaaucuu
gugaaacuccgucgugcuggggauagagcauuguaauuguugcucuucaa
cgaggaauuccuaguaagcgcaagucaucagcuugcguugauuacguccc
ugcccuuuguacacaccgcccgucgcuacuaccgauugaauggcuuagug
aggccuccggauugguuuaggaaauucuggaaccgagaagcuggucaaac
uuggucauuuagaggaaguaaaagucguaacaagguuuccguaggugaac
cugcggaaggaucau
...<<<<<.{.((((>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<...............<<.....<..<
<.......>>..>......>>........<<<<<..<<....>>..>>>>
><...<<<<<<.......{.((((.<<<....>>>..............>
>>>>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>>
..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>....
..>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<.........
.>>>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<<.
..>>>>..>>>..>....>.>.....<<<<<<<<<<<<.....>>.>>>>
>>>.>>>......<<..<...........>..>>.........<<<<<((
......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>
>>.........<<<[[.....<.<<...<<<.<<....<<<<<<<<<<..
.......<..>.............>>>>>>>>>>.....<<<<.......
.............>>>>....<<<<<.<<.......<<...<.......>
..<<<....>>>....>>......>>.>>..>>>.........<<<..<<
<<<<<<<.....)))).}..>>>>>>>>>>>>.....>>....<<<<<<.
<<...<<<<..<<..<<<<<<.<...<<<......>>>......>.>>>>
>>..>>.......<<....>>...>>>>...>>>>>.>>>...>>>...>
>.>....<<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>.
.........<<<.<<.<<<..<<<<<<<<..<<........>>.>>>>>>
>>..>>>...<<..]]>>...>>.....>>>.>>>.<<<......<<<<.
...>>>>....>>>..)))).}<<<<<.<<<<<<<..<<.<<<<<<..<<
<.<<<<<<......<<........>>..........<<<<<.<....<<<
<<........<<.<<<........>>>.>>......>>>>>...<<.<<<
..<<.<<<<<.....<<<.<<<<<....>>>...<<<......>>>...>
>.>>>....<<<<<.<<..<<<<..<<<<.<<<<<<<....>>>>>>>..
..>>>>..>>>>.>>....<<<<<<.....>>>>>>.......>>>>>..
...>>.>>>.....>>>>>>>.....>.>>>>>...>>.>>>>.>>>...
..<<<<<<<......<<......<<<.<<<<....>>>>.>>>....>>.
......>>>>>>>...........<<<<<<..........>>>>>>....
......>>>>>>....<<<<<<<<.......>>>>>>>>......>>...
>>>>>>>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<.
.<<<<..<...<<<<<<<.<.<...>.>.>>>>>>>...>..>>>>..>>
>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<<..>>
>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8cre Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution3.0 Å
Binding residue
(original residue number in PDB)
R162 R163 R165 R170 R172 R173 R176
Binding residue
(residue number reindexed from 1)
R161 R162 R164 R169 R171 R172 R175
External links
PDB RCSB:8cre, PDBe:8cre, PDBj:8cre
PDBsum8cre
PubMed
UniProtA0A1D8PK40|RL19A_CANAL Large ribosomal subunit protein eL19 (Gene Name=RPL19A)

[Back to BioLiP]