Structure of PDB 8bpx Chain BD Binding Site BS02

Receptor Information

>8bpx Chain BD (length=195) Species: 3702 (Arabidopsis thaliana)

VPATVEAVKTPNSKIVYDDHNHERYPPGDPSKRAFAYFVLSGGRFVYASV
LRLLVLKLIVSMSASKDVLALASLEVDLGSIEPGTTVTVKWRGKPVFIRR
RTEDDIKLANSVDVGSLRDPQEDSVRVKNPEWLVVVGVCTHLGCIPLPNA
GDYGGWFCPCHGSHYDISGRIRKGPAPYNLEVPTYSFLEENKLLI

Ligand information

• Ligand ID: FES
• InChI: InChI=1S/2Fe.2S
• InChIKey: NIXDOXVAJZFRNF-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04: [Fe]1S[Fe]S1
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: S1[Fe]S[Fe]1
• Formula: Fe2 S2
• Name: FE2/S2 (INORGANIC) CLUSTER
• PDB chain: 8bpx Chain BD Residue 301

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8bpx Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
• Resolution: 2.09 Å
• Binding residue (original residue number in PDB): C215 H217 L218 C220 C234 C236 H237 S239
• Binding residue (residue number reindexed from 1): C139 H141 L142 C144 C158 C160 H161 S163
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 7.1.1.8: quinol--cytochrome-c reductase.

Gene Ontology

Molecular Function

• GO:0008121 ubiquinol-cytochrome-c reductase activity
• GO:0046872 metal ion binding
• GO:0051537 2 iron, 2 sulfur cluster binding

Biological Process

• GO:1902600 proton transmembrane transport

Cellular Component

• GO:0005739 mitochondrion
• GO:0005743 mitochondrial inner membrane
• GO:0009536 plastid
• GO:0016020 membrane
• GO:0031966 mitochondrial membrane
• GO:0045275 respiratory chain complex III

External links

• PDB: RCSB:8bpx, PDBe:8bpx, PDBj:8bpx
• PDBsum: 8bpx
• PubMed: 36585502
• UniProt: Q94JS0|UCRI1_ARATH Cytochrome b-c1 complex subunit Rieske-1, mitochondrial (Gene Name=UCR1-1)