Structure of PDB 7o81 Chain BD Binding Site BS02

Receptor Information
>7o81 Chain BD (length=294) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
cFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRM
IVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCT
GLLLARRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGAFTCYLDAGLA
RTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMG
QNVADYMRYLMEEDEDAYKKQFSQYIKNNVTPDMMEEMYKKAHAAIRENP
VYEKKPKREVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAA
Ligand information
>7o81 Chain B7 (length=120) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucuacggccauaccacccugaacgcgcccgaucucgucugaucucggaa
gcuaagcagggucgggccugguuaguacuuggaugggagaccgccuggga
auaccgggugcuguaggcuu
<<<<<<<<<....<<<<<<<<.....<<<<<..............>>>..
>>....>>>>>>.>><<<<<<<.....<<.<<..<<....>>.>>.>>..
..>>>>>>>>>>>>>>>>..
Receptor-Ligand Complex Structure
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PDB7o81 Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
K8 K10 F13 K14 V18 F20 R21 R22 R24 K27 T28 Y30 R33 R50 I52 R54 T56 N57 R58 I61 Q63 I69 D72 M73 I74 N94 Y95 R152 T155 N157 K158 V204 Y207 Q222 S224 Q225 Y226 Y253 K255 K256 R259 V261 K262 K263 R265 W266 N267 R268 P269 K270 M271 L273 K276 R279
Binding residue
(residue number reindexed from 1)
K7 K9 F12 K13 V17 F19 R20 R21 R23 K26 T27 Y29 R32 R49 I51 R53 T55 N56 R57 I60 Q62 I68 D71 M72 I73 N93 Y94 R151 T154 N156 K157 V203 Y206 Q221 S223 Q224 Y225 Y252 K254 K255 R258 V260 K261 K262 R264 W265 N266 R267 P268 K269 M270 L272 K275 R278
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7o81, PDBe:7o81, PDBj:7o81
PDBsum7o81
PubMed34029205
UniProtP19949|RL5_RABIT Large ribosomal subunit protein uL18 (Gene Name=RPL5)

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