Structure of PDB 8oeq Chain BC Binding Site BS02
Receptor Information
>8oeq Chain BC (length=233) Species:
5476
(Candida albicans) [
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NPLFESTPKNFGIGQSIQPKRNLSRFVKWPEYVRLQRQKKILSLRLKVPP
SIAQFSQTLDKNTAAQAFKLLNKYRPETSAEKKERLTKEAAAIAEGKTAK
DVSPKPVVVKYGLNHVVSLIENKKAKLVLIANDVDPIELVVFLPALCKKM
GVPYAIVKGKARLGTLVHKKTSAVAALTEVNSADEAELSKLISTINANYI
EKYEENRKHWGGGIMGSKANDKIAKKAKAAAAA
Ligand information
>8oeq Chain AU (length=158) [
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aaacuuucaacaacggaucucuugguucucgcaucgaugaagaacgcagc
gaaaugcgauacguaauaugaauugcagauauucgugaaucaucgaaucu
uugaacgcacauugcgcccucugguauuccggagggcaugccuguuugag
cgucguuu
.........................................<<<<<<.((
.....>>>.....<.<<<<.....))............>>.>>..>...>
>>....<<.....>><<<<<<<<<....>>>>>>>>>.............
........
Receptor-Ligand Complex Structure
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PDB
8oeq
Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution
3.3 Å
Binding residue
(original residue number in PDB)
Y56 V57 Q60 R61 K64 K85 R186
Binding residue
(residue number reindexed from 1)
Y32 V33 Q36 R37 K40 K61 R162
External links
PDB
RCSB:8oeq
,
PDBe:8oeq
,
PDBj:8oeq
PDBsum
8oeq
PubMed
UniProt
A0A8H6C337
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