Structure of PDB 4v66 Chain BC Binding Site BS02

Receptor Information
>4v66 Chain BC (length=94) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAIELDHDKVMNM
QAKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLQHIDFVRA
Ligand information
>4v66 Chain BB (length=2903) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguuaagcgacuaagcguacacgguggaugcccuggcagucagaggcgau
gaaggacgugcuaaucugcgauaagcgucgguaaggugauaugaaccguu
auaaccggcgauuuccgaauggggaaacccaguguguuucgacacacuau
cauuaacugaauccauagguuaaugaggcgaaccgggggaacugaaacau
cuaaguaccccgaggaaaagaaaucaaccgagauucccccaguagcggcg
agcgaacggggagcagcccagagccugaaucaguguguguguuaguggaa
gcgucuggaaaggcgcgcgauacagggugacagccccguacacaaaaaug
cacaugcugugagcucgaugaguagggcgggacacgugguauccugucug
aauauggggggaccauccuccaaggcuaaauacuccugacugaccgauag
ugaaccaguaccgugagggaaaggcgaaaagaaccccggcgaggggagug
aaaaagaaccugaaaccguguacguacaagcagugggagcacgcuuaggc
gugugacugcguaccuuuuguauaaugggucagcgacuuauauucuguag
caagguuaaccgaauaggggagccgaagggaaaccgagucuuaacugggc
guuaaguugcaggguauagacccgaaacccggugaucuagccaugggcag
guugaagguuggguaacacuaacuggaggaccgaaccgacuaauguugaa
aaauuagcggaugacuuguggcugggggugaaaggccaaucaaaccggga
gauagcugguucuccccgaaagcuauuuagguagcgccucgugaauucau
cuccggggguagagcacuguuucggcaagggggucaucccgacuuaccaa
cccgaugcaaacugcgaauaccggagaauguuaucacgggagacacacgg
cgggugcuaacguccgucgugaagagggaaacaacccagaccgccagcua
aggucccaaagucaugguuaagugggaaacgaugugggaaggcccagaca
gccaggauguuggcuuagaagcagccaucauuuaaagaaagcguaauagc
ucacuggucgagucggccugcgcggaagauguaacggggcuaaaccaugc
accgaagcugcggcagcgacgcuuaugcguuguuggguaggggagcguuc
uguaagccugcgaaggugugcugugaggcaugcuggagguaucagaagug
cgaaugcugacauaaguaacgauaaagcgggugaaaagcccgcucgccgg
aagaccaaggguuccuguccaacguuaaucggggcagggugagucgaccc
cuaaggcgaggccgaaaggcguagucgaugggaaacagguuaauauuccu
guacuugguguuacugcgaaggggggacggagaaggcuauguuggccggg
cgacgguugucccgguuuaagcguguaggcugguuuuccaggcaaauccg
gaaaaucaaggcugaggcgugaugacgaggcacuacggugcugaagcaac
aaaugcccugcuuccaggaaaagccucuaagcaucagguaacaucaaauc
guaccccaaaccgacacagguggucagguagagaauaccaaggcgcuuga
gagaacucgggugaaggaacuaggcaaaauggugccguaacuucgggaga
aggcacgcugauauguaggugaggucccucgcggauggagcugaaaucag
ucgaagauaccagcuggcugcaacuguuuauuaaaaacacagcacugugc
aaacacgaaaguggacguauacggugugacgccugcccggugccggaagg
uuaauugaugggguuagcgcaagcgaagcucuugaucgaagccccgguaa
acggcggccguaacuauaacgguccuaagguagcgaaauuccuugucggg
uaaguuccgaccugcacgaauggcguaaugauggccaggcugucuccacc
cgagacucagugaaauugaacucgcugugaagaugcaguguacccgcggc
aagacggaaagaccccgugaaccuuuacuauagcuugacacugaacauug
agccuugauguguaggauaggugggaggcuuugaaguguggacgccaguc
ugcauggagccgaccuugaaauaccacccuuuaauguuugauguucuaac
guugacccguaauccggguugcggacagugucugguggguaguuugacug
gggcggucuccuccuaaagaguaacggaggagcacgaagguuggcuaauc
cuggucggacaucaggagguuagugcaauggcauaagccagcuugacugc
gagcgugacggcgcgagcaggugcgaaagcaggucauagugauccggugg
uucugaauggaagggccaucgcucaacggauaaaagguacuccggggaua
acaggcugauaccgcccaagaguucauaucgacggcgguguuuggcaccu
cgaugucggcucaucacauccuggggcugaaguaggucccaaggguaugg
cuguucgccauuuaaagugguacgcgagcuggguuuagaacgucgugaga
caguucggucccuaucugccgugggcgcuggagaacugaggggggcugcu
ccuaguacgagaggaccggaguggacgcaucacugguguucggguuguca
ugccaauggcacugcccgguagcuaaaugcggaagagauaagugcugaaa
gcaucuaagcacgaaacuugccccgagaugaguucucccugacccuuuaa
ggguccugaaggaacguugaagacgacgacguugauaggccgggugugua
agcgcagcgaugcguugagcuaaccgguacuaaugaaccgugaggcuuaa
ccu
<<<<<<<<.......<<.<<<<.<..........<<<<<<<<<<.<<...
...<<<...................<<<<<....<<<.......>>>...
.....>>>>>...>>>....<<......>><<<<<<<....>>>>>>>.<
<<<<<<<<<......>.>>>>>>>>>.>>...<<<<.<............
........>>>>..>........<<....>>...<<<<<...........
.......>>>>>...<<<..<<<<......<<<<<<<<<<<...<.....
.<<<........>>>.........<<<.......>>>.....>.....>>
>>>>>>>>>...>>>>........<...<<.............>>...>.
......<<<<..(((.>>.>>..>>>.......>.>>>>>>>.>>.....
.................................<<<<.....>>>>....
...............>.>>>>.>>.........<<....<<<<......>
>>>....>>...................<<........<<.....<<<<<
<....<...<<.....>>...>.....<<....>>..<<<.......>>>
.....>>>>>>.....>>..<<.....<<<...............<....
<<<...<<<<<<......>>>>>>.>>...>...................
................>.........<<.......>>.........>>>.
.......>>..<<<<<........<<....>>.....<<<<<<<...<<<
<<<<<.<....<<<...<<..<<<<...<<<<<<<.....>>>>>.>>..
.>>>>..>>..>>.>.....>>>>>>.>>>...>>>>>>>..........
<..<........>..>........................<<<<.<<...
.....(......<<<<<<...........<<...<<<<..<<......<.
<<<<<.<<<..<<<.........>>>..>>>........<<<......>>
>..>>>>>.>..>>..>>>>..>>............)......>>>>>>.
.......>>>>>>.<<<<<<<<....>>>>>>>>......>>>>>.<..<
<<....<.............<<....>>..........>...>>>...>.
.........>>................<<<<.......>>>>..<<<<..
.............<<<<<...............>>>>.>.....<<..<<
<...<<<...<<<....>>>...>>>...>>>..<<<<..........>>
>>..<<<<<<<<<<<<<...<<<<....<<<<..<<<..<<<<<.<<<<<
....[[....>>>>>.....<<<.....<<<<<<<<<<<.<<.....>>>
>>>>>>>..>>>.....>>>........<<<<<....>>>>>....>>>>
>...>>>...>>.>>........>>>>...>>....>>>>>>>>>>>..>
>.........................<<.........>>..>>>>...<<
.........<<......................<<...............
..>>..<<<<<<.....<.<...<<<<.....>>>>...>.>...>>>>>
>............<.<.<<.........................<<<<..
....................>>>>.....<<<<...<....<<<<<..<<
.........<<<<<<.<<....>>..>>>>>>.........>>>>>>>..
...>.<<<<<<.......>>>>>>......................<...
........>............>>>>.......>>.>.>..........>>
......>>..................................<<<<.<..
......................<<....<...<<<.<<<<..<<<<<<<<
<<<.<<<............<<<<<..<<.......<<<<<<<......>>
>>>>>....>>............>>>>>...>>>.>>>>>>>>>>>...<
<<.<<<<<.......>>>>>>>>.....>>>>.>>>....>....<<<..
.....>>>.<<<<<...........>>>>>........((.[((.....<
<<<.........>>>>...........<<<.......)).]))...<<<<
...<<<....>>>...>>>>..............>>>........<<<<<
<.<<...)))..>>>>>>>>..............>>..............
....<......<<<<<...<.........>...>>>>>.......>....
......<..<.........<<<..<<<<......>>.>>...>>>..<<<
.......>>>.................>....>....<<..<<......>
>...>>.............>.>>>>....<<<<<<<...<<<<...<<<<
<<...............>>>>>.>..<<<<....<<<.....<<<..<<<
..]]..>>>....>>>.....>>>..>>>>.....<<....<<<<<....
.......>>>>>....>>..>>>>.......>>>>>>>..<<<<<<...>
>>>>>.....<<.......................<..<<<<<..<<...
.<<<<<....>>>>>...>>...>>>>>...>.....>>.....>>>>>>
>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v66 The Structure of the E. coli Ribosome Before and After Accommodation: Implications for Proofreading
Resolution9.0 Å
Binding residue
(original residue number in PDB)		K46 N49 K83 P84 K85
Binding residue
(residue number reindexed from 1)		K46 N49 K83 P84 K85
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0009314 response to radiation
GO:0017148 negative regulation of translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v66, PDBe:4v66, PDBj:4v66
PDBsum4v66
PubMed
UniProtP68919|RL25_ECOLI Large ribosomal subunit protein bL25 (Gene Name=rplY)

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