Structure of PDB 7nzp Chain BBB Binding Site BS02

Receptor Information
>7nzp Chain BBB (length=182) Species: 2012527 (Thermofilum sp. ex4484_79) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMMLTKELVKEAREKAIRMLEKACIAITDEEKEKIEVTDFGLGVLYTFGL
EILVYVNNERYCAKELVMFPRQICPEHRHPPIGSYLGKQETFRCRWGEVY
LYVPGTPTPNPRARIPEEKKRYFTVWHEIVLRPGEQYTIPPNTLHWFQAG
DEGAIVSEFSSQSIDEKDIFTDPNVKRIPEIV
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7nzp Chain BBB Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7nzp Biochemical and Structural Characterisation of a Novel D-Lyxose Isomerase From the Hyperthermophilic Archaeon Thermofilum sp.
Resolution1.345 Å
Binding residue
(original residue number in PDB)		H75 H77 E88 H143
Binding residue
(residue number reindexed from 1)		H77 H79 E90 H145
Annotation score1
Enzymatic activity
Enzyme Commision number 5.3.1.15: D-lyxose ketol-isomerase.
Gene Ontology
Molecular Function
GO:0016853 isomerase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7nzp, PDBe:7nzp, PDBj:7nzp
PDBsum7nzp
PubMed34422783
UniProtA0A256XLS3|DLYKI_THEX4 D-lyxose ketol-isomerase (Gene Name=B6U94_07925)

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