Structure of PDB 4w2h Chain B3 Binding Site BS02
Receptor Information
>4w2h Chain B3 (length=59) Species:
300852
(Thermus thermophilus HB8) [
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PRLKVKLVKSPIGYPKDQKAALKALGLRRLQQERVLEDTPAIRGNVEKVA
HLVRVEVVE
Ligand information
>4w2h Chain BB (length=120) [
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ucccccgugcccauagcggcguggaaccacccguucccauuccgaacacg
gaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccuggga
gaguaggucggugcggggga
.<<<<<<<<<<....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>><<<.......<<<<<<<<....>>>>>>>>..
.....>>>.>>>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB
4w2h
Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Resolution
2.7 Å
Binding residue
(original residue number in PDB)
Y15 Q19 H52
Binding residue
(residue number reindexed from 1)
Y14 Q18 H51
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003735
structural constituent of ribosome
Biological Process
GO:0006412
translation
Cellular Component
GO:0005840
ribosome
GO:0015934
large ribosomal subunit
GO:0022625
cytosolic large ribosomal subunit
GO:1990904
ribonucleoprotein complex
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External links
PDB
RCSB:4w2h
,
PDBe:4w2h
,
PDBj:4w2h
PDBsum
4w2h
PubMed
25306919
UniProt
Q5SHQ6
|RL30_THET8 Large ribosomal subunit protein uL30 (Gene Name=rpmD)
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