Structure of PDB 8xrf Chain B Binding Site BS02

Receptor Information
>8xrf Chain B (length=774) Species: 10498 (African swine fever virus BA71V) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VDVDKYTRARNAGGKRAQDCMLLAAEGDSALSLLRTGLTLGKSNPSGPSF
DFCGMISLGGVIMNACKKVTNITIMVRNEQLTNNKVLQGIVQVLGLDFNC
HYKTQEERAKLRYGCIVACVDQDLDGCGKILGLLLAYFHLFWPQLIIHGF
VKRLLTPLIRVYEKGKTMPVEFYYEQEFDAWAKKQTSLVNHTVKYYKGLA
AHDTHEVKSMFKHFDNMVYTFTLDDSAKELFHIYFGGESELRKRELCTGV
VPLTETQTQSIHSVRRIPCSLHLQVDTKAYKLDAIERQIPNFLDGMTRAR
RKILAGGVKCFASNNRERKVFQFGGYVADHMFYHHGDMSLNTSIIKAAQY
YPGSSHLYPVFIGIGSFGSRHLGGKDAGSPRYISVQLASEFIKTMFPAED
SWLLPYVFEDGQRAEPEYYVPVLPLAIMEYGANPSEGWKYTTWARQLEDI
LALVRAYVDKDNPKHELLHYAIKHKITILPLRPSNYNFKGHLKRFGQYYY
SYGTYDISEQRNIITITELPLRVPTVAYIESIKKSSNRMTFIEEIIDYSS
SETIEILVKLKPNSLNRIVEEFKETEEQDSIENFLRLRNCLHSHLNFVKP
KGGIIEFNSYYEILYAWLPYRRELYQKRLMREHAVLKLRIIMETAIVRYI
NESAELNLSHYEDEKEASRILSEHGFPPLNHTLIISPEFASIEELNQKAL
QGCYTYILSLQARELLIAAKTRRVEKIKKMQARLDKVEQLLQESPFPGAS
VWLEEIDAVEKAIIKGRNTQWKFH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8xrf The crystal structure of AsfvTopII in complex with G-DNA
Resolution2.94 Å
Binding residue
(original residue number in PDB)
E438 V473 D543 R705 R718 Y751 H753 G754 S761 K793 A850 P852 K857
Binding residue
(residue number reindexed from 1)
E26 V61 D125 R287 R300 Y333 H335 G336 S343 K375 A432 P434 K439
External links
PDB RCSB:8xrf, PDBe:8xrf, PDBj:8xrf
PDBsum8xrf
PubMed
UniProtQ00942|TOP2_ASFB7 DNA topoisomerase 2 (Gene Name=TOP)

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