Structure of PDB 8vq2 Chain B Binding Site BS02

Receptor Information
>8vq2 Chain B (length=1046) Species: 10298 (Human alphaherpesvirus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NFYNPYLAPVGPTQRHTYYSECDEFRFIAPRVLDEDAPPEKRAGVHDGHL
KRAPKVYCGGDERDVLRVGSGGFWPRRSRLWGGVDHAPAGFNPTVTVFHV
YDILENVEHAYGMRAAQFHARFMDAITPTGTVITLLGLTPEGHRVAVHVY
GTRQYFYMNKEEVDRHLQCRAPRDLCERMAAALRESPGASFRGISADHFE
AEVVERTDVYYYETRPALFYRVYVRSGRVLSYLCDNFCPAIKKYEGGVDA
TTRFILDNPGFVTFGWYRLKPGRNNTLAQPRAPMAFGTSSDVEFNCTADN
LAIEGGMSDLPAYKLMCFDIACKAGGEDELAFPVAGHPEDLVIQISCLLY
DLSTTALEHVLLFSLGSCDLPESHLNELAARGLPTPVVLEFDSEFEMLLA
FMTLVKQYGPEFVTGYNIINFDWPFLLAKLTDIYKVPLDGYGRMNGRGVF
RVWDIKRSKIKVNGMVNIDMYGIITDKIKLSSYKLNAVAEAVLKDKKKDL
SYRDIPAYYAAGPAQRGVIGEYCIQDSLLVGQLFFKFLPHLELSAVARLA
GINITRTIYDGQQIRVFTCLLRLADQKGFILPDTQHVGYQGARVHDPTSG
FHVNPVVGFDFASLYPSIIQAHNLCFSTLSLRADAVAHLEAGKDYLEIEV
GGRRLFFVKAHVRESLLSILLRDWLAMRKQIRSRIPQSSPEEAVLLDKQQ
AAIKVVCNSVYGFTGVQHGLLPCLHVAATVTTIGREMLLATREYVHARWA
AFEQLLADFPEAADMRAPGPYSMRIIYGDTDSIFVLCRGLTAAGLTAMGD
KMASHISRALFLPPIKLECEKTFTKLLLIAKKKYIGVIYGGKMLIKGVDL
VRKNNCAFINRTSRALVDLLFYDDTVSGAAAALAERPAEEWLARPLPEGL
QAFGAVLVDAHRRITDPERDIQDFVLTAELSRHPRAYTNKRLAHLTVYYK
LMARRAQVPSIKDRIPYVIVAQTREVEETVARLAALRESELAEDPAYAIA
HGVALNTDYYFSHLLGAACVTFKALFGNNAKITESLLKRFIPEVWH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8vq2 Discovery of Broad-Spectrum Herpes Antiviral Oxazolidinone Amide Derivatives and Their Structure-Activity Relationships.
Resolution3.829 Å
Binding residue
(original residue number in PDB)
K534 D888 K939 Y941 K953 R959 N961 E1036 S1038 R1039 Y1044 T1045 N1046 R1071
Binding residue
(residue number reindexed from 1)
K479 D781 K832 Y834 K846 R852 N854 E929 S931 R932 Y937 T938 N939 R964
External links