Structure of PDB 8vpg Chain B Binding Site BS02

Receptor Information
>8vpg Chain B (length=551) Species: 1496 (Clostridioides difficile) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGIYYTPKIIVDYIVKKTLKNHDIIKNPYPRILDISCGCGNFLLEVYDIL
YDLFEENIYELKKKYDENYWTVDNIHRHILNYCIYGADIDEKAISILKDS
LTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFDYIVGNPPYIGHKKLEK
KYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVITPRYFLESL
SGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETF
YNKIQEKCKYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCW
IKSKNINKYIVDKSEYRLIYSNDIDNENTNKRILDEIIGLYKTKLENRRE
CKSGIRKWYELQWGREKLFFERKKIMYPYKSNENRFAIDYDNNFSSADVY
SFFIKEEYLDKFSYEYLVGILNSSVYDKYFKITAKKMSKNIYDYYPNKVM
KIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIKMDNLIMDSLG
I
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8vpg Quinoline-based compounds can inhibit diverse enzymes that act on DNA
Resolution3.05 Å
Binding residue
(original residue number in PDB)		H171 K172 K179 D192 K193 K254 I349 G351 C352 D353 K378 S379 K380 K420 R425 Q438 W439 Y455 K456
Binding residue
(residue number reindexed from 1)		H145 K146 K153 D166 K167 K228 I323 G325 C326 D327 K352 S353 K354 K394 R399 Q412 W413 Y429 K430
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