Structure of PDB 8uyi Chain B Binding Site BS02

Receptor Information
>8uyi Chain B (length=369) Species: 121224 (Pediculus humanus corporis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DELEGICWEIREAVSKGVEQLQAANLDELDLGEPIAKGCNAVVYSAKLKH
QLAVKMMFNYDVESNSTAILKAMYRETVPAMSYFFKIRLPPHPNIVRMYS
VFADRNMSLFLVMKRYDCTLKEYLRDKTPNMRSSILLLSQLLEAVAHMNI
HNISHRDLKSDNILVDLSEGDAYPTIVITDFGCCLCDKQNGLVIPYRSED
QDKGGNRALMAPEIANAKPGTFSWLNYKKSDLWAVGAIAYEIFNIDNPFY
KLLSKSYKEEDLPELPDTIPFIIRNLVSNMLSRSTNKRLDCDVAATVAQL
YLWAPSSWLKENYTLPNSNEIIQWLLCLSSKVLCRRSLPEYELIASFLRR
VRLHLVRKGLKWIQELHIY
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8uyi Chain B Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8uyi Interaction of PINK1 with nucleotides and kinetin.
Resolution3.13 Å
Binding residue
(original residue number in PDB)		N339 D357
Binding residue
(residue number reindexed from 1)		N162 D180
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8uyi, PDBe:8uyi, PDBj:8uyi
PDBsum8uyi
PubMed38241364
UniProtE0W1I1|PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial (Gene Name=Pink1)

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