Structure of PDB 8uyh Chain B Binding Site BS02

Receptor Information
>8uyh Chain B (length=370) Species: 121224 (Pediculus humanus corporis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DDELEGICWEIREAVSKVEQLQAANLDELDLGEPIAKGCNAVVYSAKLKH
QLAVKMMFNYDVESNSTAILKAMYRETVPAMSYFFIRLPPHPNIVRMYSV
FADRNMSLFLVMKRYDCTLKEYLRDKTPNMRSSILLLSQLLEAVAHMNIH
NISHRDLKSDNILVDLSEGDAYPTIVITDFGCCLCDKQNGLVIPYRSEDQ
DKGGNRALMAPEIANAKPGTFSWLNYKKSDLWAVGAIAYEIFNIDNPFYD
KKLLSKSYKEEDLPELPDTIPFIIRNLVSNMLSRSTNKRLDCDVAATVAQ
LYLWAPSSWLKENYTLPNSNEIIQWLLCLSSKVLCRRSLPEYELIASFLR
RVRLHLVRKGLKWIQELHIY
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8uyh Chain B Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8uyh Interaction of PINK1 with nucleotides and kinetin.
Resolution2.84 Å
Binding residue
(original residue number in PDB)		N339 D357
Binding residue
(residue number reindexed from 1)		N161 D179
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8uyh, PDBe:8uyh, PDBj:8uyh
PDBsum8uyh
PubMed38241364
UniProtE0W1I1|PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial (Gene Name=Pink1)

[Back to BioLiP]