Structure of PDB 8u1l Chain B Binding Site BS02

Receptor Information
>8u1l Chain B (length=638) Species: 7111 (Trichoplusia ni) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESL
TDPSKLDSGKELYIKIIPNKSEGTFTIIDTGIGMTKADLVNNLGTIAKSG
TKAFMEALQAGADISMIGQFGVGFYSCYLVADRVTVHSKHNDDEQYMWES
SAGGSFTVRTDHGEPLGRGTKIVLHIKEDLAEYLEVNKIKEIVKKHSQFI
GYPIKLTVEKEREKEKKKTIKEKYTEDEELNKTKPIWTRNADDITQEEYG
DFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENKKRKNN
IKLYVRRVFIMDNCEDLIPEYLNFIKGVVDSEDLPLNISREMLQQNKILK
VIRKNLVKKCLELFEELAEDKENYKKYYEQFSKNLKLGIHEDAQNRTKLA
DLLRYHTSASGDEACSLKEYVSRMKENQKHIYYITGENRDQVANSSFVER
VKKRGYEVVYMTEPIDEYVVQQMREYDGKTLVSVTKEGLELPEDEEEKKK
REEDKVKFEGLCKVMKNILDNKVEKVVVSNRLVESPCCIVTAQYGWSANM
ERIMKAQALRDTSTMGYMAAKKHLEINPDHSIVETLRQKAEADKNDKAVK
DLVILLYETALLSSGFTLDEPQVHASRIYRMIKLGLGI
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8u1l Chain B Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8u1l Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		E42 G132
Binding residue
(residue number reindexed from 1)		E33 G123
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0097718 disordered domain specific binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding
GO:0034605 cellular response to heat
GO:0050821 protein stabilization
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0032991 protein-containing complex
GO:0048471 perinuclear region of cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8u1l, PDBe:8u1l, PDBj:8u1l
PDBsum8u1l
PubMed38431713
UniProtA0A7E5VSK5

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