Structure of PDB 8tkp Chain B Binding Site BS02

Receptor Information
>8tkp Chain B (length=187) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKGGVFTREQLDEYQDCTFFTRKDIIRLYKRFYALNPHKVPTNMQGNRPA
ITTLTFEEVEKMPELKENPFKRRICEVFSEDGRGNLSFDDFLDMFSVFSE
MAPLQLKLKYAFRIYDYDGDELLGHDDLSKMIRSLTRDELSDVEVEFIIE
RIIEEADLDGDSSINFAEFEHVVSRSPDFIRTFHIRI
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8tkp Chain B Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8tkp The structure of the Caenorhabditis elegans TMC-2 complex suggests roles of lipid-mediated subunit contacts in mechanosensory transduction.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		D130 D132 D134 L136 G138 D141
Binding residue
(residue number reindexed from 1)		D116 D118 D120 L122 G124 D127
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005509 calcium ion binding
GO:0046872 metal ion binding
Biological Process
GO:0055074 calcium ion homeostasis

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Molecular Function
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Biological Process
External links
PDB RCSB:8tkp, PDBe:8tkp, PDBj:8tkp
PDBsum8tkp
PubMed38354260
UniProtQ93640

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