Structure of PDB 8sng Chain B Binding Site BS02

Receptor Information

>8sng Chain B (length=365) Species: 1028307 (Klebsiella aerogenes KCTC 2190)

DFLPFSRPSMGDAELAALREVLQSGWITTGPKNQALEEAFCQLTGNRHAI
AVSSATGGMHVTLMAMGIGPGDEVITPSQTWVSTLNMICLLGATPVMIDV
DHDNLMITPEAVEAAITSRTKAIIPVHYAGAPADIDAIRAVGERHGIPVI
EDAAHAAGTHYKGRHVGWRGTAIFSFHAIKNMTCAEGGLIVTDDDELASR
IRSLKFHGLGVDPQAEVITPGFKYNLADINAALALVQLDKLAQANQRRAE
IAQRYLRELADTPFKPLTIPAWDHQHAWHLFIIRVDEAACGISRDVLMEK
LKAMGIGTGLHFRAAHTQKYYRERFPEVSLPNTEWNSARICSIPLFPDMT
DDDVTRVITALHQLS

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 8sng Chain B Residue 405

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8sng Crystal Structure of ArnB Transferase from Klebsiella aerogenes (Lattice Translocation Disorder, P21 form)
• Resolution: 1.55 Å
• Binding residue (original residue number in PDB): L271 A272 T274 F276
• Binding residue (residue number reindexed from 1): L259 A260 T262 F264
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 2.6.1.87: UDP-4-amino-4-deoxy-L-arabinose aminotransferase.

Gene Ontology

Molecular Function

• GO:0008483 transaminase activity
• GO:0030170 pyridoxal phosphate binding
• GO:0046872 metal ion binding
• GO:0099620 UDP-4-amino-4-deoxy-L-arabinose aminotransferase

Biological Process

• GO:0000271 polysaccharide biosynthetic process
• GO:0009103 lipopolysaccharide biosynthetic process
• GO:0009245 lipid A biosynthetic process
• GO:0046493 lipid A metabolic process
• GO:0046677 response to antibiotic

External links

• PDB: RCSB:8sng, PDBe:8sng, PDBj:8sng
• PDBsum: 8sng
• UniProt: A0A0H3FL22