Structure of PDB 8qz1 Chain B Binding Site BS02

Receptor Information
>8qz1 Chain B (length=237) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHV
CVSPQELETLIQHALDADNAGVSPIGNSSSSHWDLGSAFFFAGTVITTIG
YGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARRVI
STILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVA
GGNAREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVL
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain8qz1 Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8qz1 Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation.
Resolution3.588 Å
Binding residue
(original residue number in PDB)		T172 I173 T281 V282 G283
Binding residue
(residue number reindexed from 1)		T98 I99 T192 V193 G194
Annotation score3
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8qz1, PDBe:8qz1, PDBj:8qz1
PDBsum8qz1
PubMed38755204
UniProtP57789|KCNKA_HUMAN Potassium channel subfamily K member 10 (Gene Name=KCNK10)

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