Structure of PDB 8qrn Chain B Binding Site BS02

Receptor Information

>8qrn Chain B (length=225) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

EDSTDFNDKILNEPLKHSDFFNVKELFSVRSLFDARVHLGHKAGCRHRFM
EPYIFGSRLDHDIIDLEQTATHLQLALNFTAHMAYRKGIILFISRNRQFS
YLIENMARDCGEYAHTRYFRGGMLTNARLLFGPTVRLPDLIIFLHTLNNI
FEPHVAVRDAAKMNIPTVGIVDTNCNPCLITYPVPGNDDSPLAVHLYCRL
FQTAITRAKEKRQQVEALYRLQGQK

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

8qrn Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8qrn GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Resolution	2.98 Å
Binding residue (original residue number in PDB)	H93 D224 D240 D241
Binding residue (residue number reindexed from 1)	H41 D172 D188 D189
Annotation score	4

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0032543	mitochondrial translation
GO:0061668	mitochondrial ribosome assembly

	Cellular Component
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005759	mitochondrial matrix
GO:0005763	mitochondrial small ribosomal subunit
GO:0005840	ribosome
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Cellular Component

External links

PDB	RCSB:8qrn, PDBe:8qrn, PDBj:8qrn
PDBsum	8qrn
PubMed	38969660
UniProt	Q9Y399\|RT02_HUMAN Small ribosomal subunit protein uS2m (Gene Name=MRPS2)

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