Structure of PDB 8qci Chain B Binding Site BS02

Receptor Information
>8qci Chain B (length=269) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPA
VSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGA
SKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVF
PNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFC
GPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKTLASYVA
ACQAAGVVIEDWRAQVGCE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8qci Chain B Residue 4404 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8qci VWD domain stabilization by autocatalytic Asp-Pro cleavage.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		D4087 N4219 D4221 N4223 N4226 D4227
Binding residue
(residue number reindexed from 1)		D7 N139 D141 N143 N146 D147
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8qci, PDBe:8qci, PDBj:8qci
PDBsum8qci
PubMed38380729
UniProtQ9Y6R7|FCGBP_HUMAN IgGFc-binding protein (Gene Name=FCGBP)

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