Structure of PDB 8pi8 Chain B Binding Site BS02

Receptor Information
>8pi8 Chain B (length=164) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSPEEAAHQKAVVETLLQEDPWRVAKMVKSYLQQHNIPQREVVDTTGLNQ
SHLSQHLNKGTPMKTQKRAALYTWYVRKQREVAQQFTHRNRFKWGPASQQ
ILFQAYERQKNPSKEERETLVEECNRAECIQRGVSPSQAQGLGSNLVTEV
RVYNWFANRRKEEA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pi8 Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		P129 Q130 R131 Q141 S142 S145 N149 R203 R272 K273
Binding residue
(residue number reindexed from 1)		P38 Q39 R40 Q50 S51 S54 N58 R91 R160 K161
External links
PDB RCSB:8pi8, PDBe:8pi8, PDBj:8pi8
PDBsum8pi8
PubMed38855865
UniProtP20823|HNF1A_HUMAN Hepatocyte nuclear factor 1-alpha (Gene Name=HNF1A)

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