Structure of PDB 8ow4 Chain B Binding Site BS02

Receptor Information
>8ow4 Chain B (length=296) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HHHHHHVGTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGA
VKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGK
TVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGE
TDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVER
QDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDKDK
SQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ow4 2.75 angstrom crystal structure of human NFAT1 with bound DNA
Resolution2.75 Å
Binding residue
(original residue number in PDB)		Y424 T426 K520 R522 N523 R537 K538 R572 R665
Binding residue
(residue number reindexed from 1)		Y42 T44 K138 R140 N141 R155 K156 R190 R283
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8ow4, PDBe:8ow4, PDBj:8ow4
PDBsum8ow4
PubMed
UniProtQ13469|NFAC2_HUMAN Nuclear factor of activated T-cells, cytoplasmic 2 (Gene Name=NFATC2)

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