Structure of PDB 8oq2 Chain B Binding Site BS02

Receptor Information

>8oq2 Chain B (length=381) Species: 921 (Ancylobacter novellus)

SAKILCVLYDDPVDGYPKTYARDDLPKIDHYPGGQTLPTPKAIDFTPGAL
LGSVSGELGLRKYLEANGHTFVVTSDKDGPDSVFERELVDADVVISQPFW
PAYLTPERIAKAKNLKLALTAGIGSDHVDLQSAIDRGITVAEVTYCNSIS
VAEHVVMMILGLVRNYIPSHDWARKGGWNIADCVEHSYDLEGMTVGSVGA
GRIGLAVLRRLAPFDVKLHYTQRHRLPEAVEKELGLVWHDTREDMYPHCD
VVTLNVPLHPETEHMINDETLKLFKRGAYIVNTARGKLADRDAIVRAIES
GQLAGYAGDVWFPQPAPKDHPWRTMKWEGMTPHISGTSLSAQARYAAGTR
EILECFFEGRPIRDEYLIVQGGALAGTGAKV

Ligand information

• Ligand ID: AZI
• InChI: InChI=1S/N3/c1-3-2/q-1
• InChIKey: IVRMZWNICZWHMI-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: [N-]=[N+]=[N-]
• Formula: N3
• Name: AZIDE ION
• ChEMBL: CHEMBL79455
• PDB chain: 8oq2 Chain B Residue 402

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8oq2 Binding of NADP to a formate dehydrogenase from Starkeya novella.
• Resolution: 1.91 Å
• Binding residue (original residue number in PDB): P99 F100 I124 R286 H334
• Binding residue (residue number reindexed from 1): P98 F99 I123 R285 H333
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 1.17.1.9: formate dehydrogenase.

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0008863 formate dehydrogenase (NAD+) activity
• GO:0016491 oxidoreductase activity
• GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
• GO:0051287 NAD binding

Biological Process

• GO:0042183 formate catabolic process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:8oq2, PDBe:8oq2, PDBj:8oq2
• PDBsum: 8oq2
• UniProt: D7A8L2