Structure of PDB 8om3 Chain B Binding Site BS02

Receptor Information

>8om3 Chain B (length=342) Species: 4932 (Saccharomyces cerevisiae)

PNNNDEVMLLQQKLLYDEIRSELKSLSQVPEDEILPELKKSLEQDKLSDK
EQQLEAELSDFFRNYALLNKLFDSTKPYPNLIPSANDKPYSSQELFLRQL
NHSMRTAKLGATISKVYYPHKDIFYPPLPENITVESLMSAGVHLGQSTSL
WRSSTQSYIYGEYKGIHIIDLNQTLSYLKRAAKVVEGVSESGGIILFLGT
RQGQKRGLEEAAKKTHGYYVSTRWIPGTLTNSTEISGIWEKQEIDSNDNP
TERALSPNETSKQVKPDLLVVLNPTENRNALLEAIKSRVPTIAIIDTDSE
PSLVTYPIPGNDDSLRSVNFLLGVLARAGQRGLQNRLARNNE

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 8om3 Chain B Residue 401

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8om3 METTL17 is an Fe-S cluster checkpoint for mitochondrial translation.
• Resolution: 2.87 Å
• Binding residue (original residue number in PDB): Q197 D347 D363 D364
• Binding residue (residue number reindexed from 1): Q146 D296 D312 D313
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation
• GO:0032543 mitochondrial translation

Cellular Component

• GO:0005739 mitochondrion
• GO:0005743 mitochondrial inner membrane
• GO:0005763 mitochondrial small ribosomal subunit
• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8om3, PDBe:8om3, PDBj:8om3
• PDBsum: 8om3
• PubMed: 38199006
• UniProt: P32902|RT04_YEAST Small ribosomal subunit protein uS2m (Gene Name=MRP4)