Structure of PDB 8oeu Chain B Binding Site BS02

Receptor Information
>8oeu Chain B (length=1131) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DEITPDLWQEACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVEDAPP
IDLQAPPRYLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTYSAPLY
VDITKTVIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTDRDLCELN
ECPLDPGGYFIINGSEKVLIAQEKMATNTVYVFAKKDSKYAYTGECRSCL
ENSSRPTSTIWVSMLARGAIGQRIVATLPYIKQEVPIIIVFRALGFVSDR
DILEHIIYDFEDPEMMEMVKPSLDEAFVIQEQNVALNFIGSRGAKPGVTK
EKRIKYAKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLAALGRREL
DDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQKFIDRGKDFNLE
LAIKTRIISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLSHL
RRLNSPIGRDGKLAKPRQLHNTLWGMVCPAETPEGHAVGLVKNLALMAYI
SVGSQPSPILEFLEEWSMENLEEISPAAIADATKIFVNGCWVGIHKDPEQ
LMNTLRKLRRQMDIIVSEVSMIRDIREREIRIYTDAGRICRPLLIVEKQK
LLLKKRHIDQLKEREYNNYSWQDLVASGVVEYIDTLEEETVMLAMTPDDL
QEKEVAYCSTYTHCEIHPSMILGVCASIIPFPDHNQSPRNTYQSAMGKQA
MGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIVAI
ASYTGYNQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKP
TRETCQGMRHAIYDKLDDDGLIAPGVRVSGDDVIIGKTVTLPRYTKRDCS
TFLRTSETGIVDQVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKG
TCGIQYRQEDMPFTCEGITPDIIINPHAIPSRMTIGHLIECLQGKVSANK
GEIGDATPFNDAVNVQKISNLLSDYGYHLRGNEVLYNGFTGRKITSQIFI
GPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSRDGGLRFGEMERDC
QIAHGAAQFLRERLFEASDPYQVHVCNLCGIMAIANTRTHTYECRGCRNK
TQISLVRMPYACKLLFQELMSMSIAPRMMSV
Ligand information
Receptor-Ligand Complex Structure
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PDB8oeu Structure of transcribing RNA polymerase II-Elongin complex
Resolution3.04 Å
Binding residue
(original residue number in PDB)		T527 Q533 T823 R889 R974 G1154 R1155 L1161 R1162 M1166
Binding residue
(residue number reindexed from 1)		T418 Q424 T714 R780 R854 G1034 R1035 L1041 R1042 M1046
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0001055 RNA polymerase II activity
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0003968 RNA-dependent RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0006366 transcription by RNA polymerase II
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005665 RNA polymerase II, core complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8oeu, PDBe:8oeu, PDBj:8oeu
PDBsum8oeu
PubMed37932450
UniProtI3LGP4

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