Structure of PDB 8k1j Chain B Binding Site BS02

Receptor Information
>8k1j Chain B (length=242) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGK
YNISSEDYRQLELVILQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAP
GTDAGKAFCMFYAVLGIPLTLVMFQSLGERMNTFVRYLLKRIKKCCDVSM
ENMVTVGFFSCMGTLCIGAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYV
ALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLNLVVLRFLT
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0
[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain8k1j Chain A Residue 305 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8k1j Human TWIK-related acid-sensitive potassium channel TASK3 at pH 7.4,200 mM KCl
Resolution3.0 Å
Binding residue
(original residue number in PDB)
G95 Y96 G97 G201 F202 G203
Binding residue
(residue number reindexed from 1)
G94 Y95 G96 G195 F196 G197
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005267 potassium channel activity
Biological Process
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8k1j, PDBe:8k1j, PDBj:8k1j
PDBsum8k1j
PubMed38630723
UniProtQ9NPC2|KCNK9_HUMAN Potassium channel subfamily K member 9 (Gene Name=KCNK9)

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