Structure of PDB 8jt1 Chain B Binding Site BS02

Receptor Information
>8jt1 Chain B (length=532) Species: 673 (Grimontia hollisae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QCDLSQFQTTSSNQLMAAIRQQGASCVNALFSADTGVQEAAFSSNHMYNV
AQYTRTLAQQYAGGGSDELEALYLYLRAGYYAEFYNSNITFLSWVTPAVK
GAVDAFVQNAHFYDNGDAHGKVLNEVIITMDSAGLQHAYLDVVTQWLTRW
NAQYAEHWYMRNAVNGVFTLLFGGQWNNQYTSLIGEQTALVTALQAFALD
RTKVNSPTEFMAANAARELGRLARYTDATIAPKVTEGLTAIFGQYPSYGD
GDAIWLGAADTASYYADCSQFNICGFEDALRDAALNQTFICSDTIKIRSQ
DMSQAQHLAACDKMAYEESFFHTTLETGNQPVADDHNTQLQVNIFNSDTD
YGKYAGPIFGIDTNNGGMYLEGNPANVGNIPNFIAYEASYANPDHFVWNL
EHEYVHYLDGRFNMYGDFGTPTELVVWWSEGVAEYVSRVNDNPQAIATIQ
DGSTYTLAQVFDTTYDGFDVDRIYRWGYLAVRFMFERHPDEVQRMLSATR
QGRWAEYKAIISGWANQYQSEFAQWTEALAKG
Ligand information
Receptor-Ligand Complex Structure
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PDB8jt1 Insights into the catalytic mechanism of Grimontia hollisae collagenase through structural and mutational analyses.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		N118 F121 R167 Y171 F174 E215 I218 D221 S222
Binding residue
(residue number reindexed from 1)		N28 F31 R77 Y81 F84 E125 I128 D131 S132
Enzymatic activity
Enzyme Commision number 3.4.24.3: microbial collagenase.
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8jt1, PDBe:8jt1, PDBj:8jt1
PDBsum8jt1
PubMed37698340
UniProtF7IZI6

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