Structure of PDB 8jhf Chain B Binding Site BS02

Receptor Information
>8jhf Chain B (length=84) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RMVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRD
AVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Ligand information
>8jhf Chain J (length=160) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggaacaggatgtatatatctgacacgtgcctggagactagggagtaatcc
ccttggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtg
ctagagctgtctacgaccaattgagcggcctcggcaccgggattctccag
gggatcggat
Receptor-Ligand Complex Structure
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PDB8jhf Structural basis of nucleosomal H4K20 recognition and methylation by SUV420H1 methyltransferase
Resolution3.68 Å
Binding residue
(original residue number in PDB)
R45 S47 K79 T80
Binding residue
(residue number reindexed from 1)
R27 S29 K61 T62
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity

View graph for
Molecular Function
External links
PDB RCSB:8jhf, PDBe:8jhf, PDBj:8jhf
PDBsum8jhf
PubMed38052811
UniProtP62805|H4_HUMAN Histone H4 (Gene Name=H4C1)

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