Structure of PDB 8j1j Chain B Binding Site BS02

Receptor Information
>8j1j Chain B (length=387) Species: 1765684 (Sulfoacidibacillus thermotolerans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIKVYRYEIVKPLDLDWKEFGTILRQLQQETRFALNKATQLAWEWMGYSS
DYKDNHGEILGYTNVHGYAYHTIKTKAYRLNSGNLSQTIKRATDRFKAYQ
KEILRGDMSIPSYKRDIPLDLIKENISVNRMNHGDYIASLSLLSNPAKQE
MNVKRKISVIIIVRGAGKTIMDRILSGEYQVHASQIIHDDRKNKWYLNIS
YDFEPQTRVLDLNKIMGIDLGVAVAAYMAFQHTPARYKLEGGEIENFRRQ
VESRRISMLKPIEQLRDKIANFRDTTNHRYSRYIVDMAIKMGCGTIQMED
LDIGSRFLQNWTYYDLQQKIIYKAEEAGIKVIKIDPQYTSQRCSECGNID
GQAIFKCRACGYEANADYNAARNIAIPNIDKIIAESI
Ligand information
>8j1j Chain C (length=112) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ucgucgguucagcgacgauaagccgagaagugccaauaaaacuguuaagu
gguuugguaacgcucgguaagguccgaaaggagaaccacugaacggaaau
uaggugcgcuug
<<<<<<.(((((>>>>>>...<<<<<<..<<<<<<<....<<<....>>>
...>>>>>.>>.>>>>>>..<<<<<....>>...>>>.))))).......
............
Receptor-Ligand Complex Structure
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PDB8j1j Minimal and most efficient genome editing Cas enzyme
Resolution2.91 Å
Binding residue
(original residue number in PDB)		K3 N70 H72 G73 Y76 S92 K96 K103 K107 K129 R197 P240 G248 E249 N252 F253 R255 Q256 S259 R260 K293 N296
Binding residue
(residue number reindexed from 1)		K3 N64 H66 G67 Y70 S86 K90 K97 K101 K123 R191 P234 G242 E243 N246 F247 R249 Q250 S253 R254 K268 N271
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8j1j, PDBe:8j1j, PDBj:8j1j
PDBsum8j1j
PubMed
UniProtA0A2U3D0N8|CS12F_SULT2 CRISPR-associated endodeoxyribonuclease Cas12f1 (Gene Name=cas12f1)

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