Structure of PDB 8ij9 Chain B Binding Site BS02

Receptor Information
>8ij9 Chain B (length=166) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLED
RTVRLQLWDTAGLERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWID
DVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKELSVMFIETSAKT
GYNVKQLFRRVASALP
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8ij9 Chain B Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8ij9 Structural basis of ELKS/Rab6B interaction and its role in vesicle capturing enhanced by liquid-liquid phase separation.
Resolution2.04 Å
Binding residue
(original residue number in PDB)		T27 T45
Binding residue
(residue number reindexed from 1)		T18 T36
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:8ij9, PDBe:8ij9, PDBj:8ij9
PDBsum8ij9
PubMed37172719
UniProtP61294|RAB6B_MOUSE Ras-related protein Rab-6B (Gene Name=Rab6b)

[Back to BioLiP]