Structure of PDB 8h7a Chain B Binding Site BS02
Receptor Information
>8h7a Chain B (length=77) Species:
9606
(Homo sapiens) [
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VKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQL
ELSVKDGTILKVSNKGLNSYKDPDNPG
Ligand information
>8h7a Chain D (length=13) [
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ggtccgtcggacc
Receptor-Ligand Complex Structure
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PDB
8h7a
The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.
Resolution
1.92 Å
Binding residue
(original residue number in PDB)
Q23 K24 Q25
Binding residue
(residue number reindexed from 1)
Q22 K23 Q24
Enzymatic activity
Enzyme Commision number
2.3.1.48
: histone acetyltransferase.
Gene Ontology
Molecular Function
GO:0003677
DNA binding
View graph for
Molecular Function
External links
PDB
RCSB:8h7a
,
PDBe:8h7a
,
PDBj:8h7a
PDBsum
8h7a
PubMed
36537216
UniProt
Q92794
|KAT6A_HUMAN Histone acetyltransferase KAT6A (Gene Name=KAT6A)
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