Structure of PDB 8gsg Chain B Binding Site BS02

Receptor Information
>8gsg Chain B (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Ligand information
Ligand IDCRS
InChIInChI=1S/C7H8O/c1-6-3-2-4-7(8)5-6/h2-5,8H,1H3
InChIKeyRLSSMJSEOOYNOY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04Oc1cc(ccc1)C
OpenEye OEToolkits 1.5.0Cc1cccc(c1)O
CACTVS 3.341Cc1cccc(O)c1
FormulaC7 H8 O
NameM-CRESOL
ChEMBLCHEMBL298312
DrugBankDB01776
ZINCZINC000000897141
PDB chain8gsg Chain B Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8gsg T3R3 insulin with single Zn
Resolution2.05 Å
Binding residue
(original residue number in PDB)		V2 Q4
Binding residue
(residue number reindexed from 1)		V2 Q4
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:8gsg, PDBe:8gsg, PDBj:8gsg
PDBsum8gsg
PubMed
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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