Structure of PDB 8gju Chain B Binding Site BS02

Receptor Information
>8gju Chain B (length=330) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DKEQRFVDKLYTGLIQGQRACLAEAITLVESTHSRKKELAQVLLQKVLLY
HREQEQSNKGKPLAFRVGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAV
DPSSCTSGGSLLGDKTRMTELSRDMNAYIRPSPTRGTLGGVTRTTNEAIL
LCEGAGYDIILIETVGVGQSEFAVADMVDMFVLLLPPAGGGIKRGIIEMA
DLVAVTKSDGDLIVPARRIQAEYVSALKLLRKRSQVWKPKVIRISARSGE
GISEMWDKMKDFQDLMLASGELTAKRRKQQKVWMWNLIQESVLEHFRTHP
TVREQIPLLEQKVLIGALSPGLAADFLLKA
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8gju Chain B Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8gju Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B 12 delivery and repair.
Resolution2.79 Å
Binding residue
(original residue number in PDB)		S157 D193 E242
Binding residue
(residue number reindexed from 1)		S78 D114 E163
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.-.-
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:8gju, PDBe:8gju, PDBj:8gju
PDBsum8gju
PubMed37468522
UniProtQ8IVH4|MMAA_HUMAN Methylmalonic aciduria type A protein, mitochondrial (Gene Name=MMAA)

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