Structure of PDB 8ejp Chain B Binding Site BS02

Receptor Information

>8ejp Chain B (length=56) Species: 9258 (Ornithorhynchus anatinus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ARRKRTTFNKTQLEILVKSFNKDPYPGIGVREHLASLIQIPESRIQVWFQ
NRRARQ

Ligand information

>8ejp Chain D (length=17) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

tgutgattagattacgc

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8ejp Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein.
Resolution	2.174 Å
Binding residue (original residue number in PDB)	R22 R23 R25 T26 F28 R64 W68 N71 R72 R75
Binding residue (residue number reindexed from 1)	R2 R3 R5 T6 F8 R44 W48 N51 R52 R55

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003677	DNA binding

View graph for
Molecular Function

External links

PDB	RCSB:8ejp, PDBe:8ejp, PDBj:8ejp
PDBsum	8ejp
PubMed	37744032
UniProt	A0A6I8NF41

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