Structure of PDB 8efv Chain B Binding Site BS02

Receptor Information
>8efv Chain B (length=314) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDLALRPKTLDEYIGQERLKQKLRVYLEAAKARKEPLEHLLLFGPPGLGK
TTLAHVIAHELGVNLRVTSGPAIPGDLAAILANSLEEGDILFIDEIHRLS
RQAEEHLYPAMEDFVMDIVIGQGPAARTIRLELPRFTLIGATTRPGLITA
PLLSRFGIVEHLEYYTPEELAQGVMRDARLLGVRITEEAALEIGRRSRGT
MRVAKRLFRRVRDFAQVAGEEVITRERALEALAALGLDELGLEKRDREIL
EVLILRFGGGPVGLATLATALSEDPGTLEEVHEPYLIRQGLLKRTPRGRV
ATELAYRHLGYPPP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8efv Structure of single homo-hexameric Holliday junction ATP-dependent DNA helicase RuvB motor
Resolution2.97 Å
Binding residue
(original residue number in PDB)		V265 T269 P299 R300 G301 R302
Binding residue
(residue number reindexed from 1)		V262 T266 P296 R297 G298 R299
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0000400 four-way junction DNA binding
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0009378 four-way junction helicase activity
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005737 cytoplasm
GO:0048476 Holliday junction resolvase complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8efv, PDBe:8efv, PDBj:8efv
PDBsum8efv
PubMed
UniProtQ5SL87|RUVB_THET8 Holliday junction branch migration complex subunit RuvB (Gene Name=ruvB)

[Back to BioLiP]