Structure of PDB 8df9 Chain B Binding Site BS02

Receptor Information
>8df9 Chain B (length=845) Species: 2320 (Methanopyrus kandleri) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALVYDAEFVGSEREFEEERETFLKGVKAYDGVLATRYLMERSSSAKNDEE
LLELHQNFILLTGSYACSIDPTEDRYQNVIVRGVNFDERVQRLSTGGSPA
RYAIVYRRGWRAIAKALDIDEEDVPAIEVRAVKRNPLQPALYRILVRYGR
VDLMPVTVDEVPPEMAGEFERLIERYDVPIDEKEERILEILRENPWTPHD
EIARRLGLSVSEVEGEKDPESSGIYSLWSRVVVNIEYDERTAKRHVKRRD
RLLEELYEHLEELSERYLRHPLTRRWIVEHKRDIMRRYLEQRIVECALKL
QDRYGIREDVALCLARAFDGSISMIATTPYRTLKDVCPDLTLEEAKSVNR
TLATLIDEHGLSPDAADELIEHFESIAGILATDLEEIERMYEEGRLSEEA
YRAAVEIQLAELTKKEGVGRKTAERLLRAFGNPERVKQLAREFEIEKLAS
VEGVGERVLRSLVPGYASLISIRGIDRERAERLLKKYGGYSKVREAGVEE
LREDGLTDAQIRELKGLKTLESIVGDLEKADELKRKYGSASAVRRLPVEE
LRELGFSDDEIAEIKGIPKKLREAFDLETAAELYERYGSLKEIGRRLSYD
DLLELGATPKAAAEIKGPEFKFLLNIEGVGPKLAERILEAVDYDLERLAS
LNPEELAEKVEGLGEELAERVVYAARERVESRRKSGRQERSEEEWKEWLE
RKVGEGRARRLIEYFGSAGEVGKLVENAEVSKLLEVPGIGDEAVARLVPG
YKTLRDAGLTPAEAERVLKRYGSVSKVQEGATPDELRELGLGDAKIARIL
GLRSLVNARLDVDTAYELARRYGSVSAAELRELGLSDRAIARIAG
Ligand information
Receptor-Ligand Complex Structure
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PDB8df9 Structures of topoisomerase V in complex with DNA reveal unusual DNA binding mode and novel relaxation mechanism.
Resolution3.24 Å
Binding residue
(original residue number in PDB)		G454 V455 G456 E457 R458 V459 R474 G707 R756
Binding residue
(residue number reindexed from 1)		G453 V454 G455 E456 R457 V458 R473 G706 R755
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:8df9, PDBe:8df9, PDBj:8df9
PDBsum8df9
PubMed35969036
UniProtQ977W1

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