Structure of PDB 8c5u Chain B Binding Site BS02

Receptor Information
>8c5u Chain B (length=329) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVPIPGIKDISKLKFFYGFKYLWNPTVYNKIFDKLDLTKTYKHPEELKVL
DLYPGVGIQSAIFYNKYCPRQYSLLEKRSSLYKFLNAKFEGSPLQILKRD
PYDWSTYSNLIDEERIFVPEVQSSDHINDKFLTVANVTGEGSEGLIMQWL
SCIGNKNWLYRFGKVKMLLWMPSTTARKLLARPGMHSRSKCSVVREAFTD
TKLIAISDANELKGFDSQCIEEWDPILFSAAEIWPTKGKPIALVEMDPID
FDFDVDNWDYVTRHLMILKRTPLNTVMDSLGHGGQQYFNSRITDKDLLKK
CPIDLTNDEFIYLTKLFMEWPFKPDILMD
Ligand information
Receptor-Ligand Complex Structure
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PDB8c5u Structures illustrate step-by-step mitochondrial transcription initiation
Resolution3.62 Å
Binding residue
(original residue number in PDB)		H187 R271 T272
Binding residue
(residue number reindexed from 1)		H186 R270 T271
Enzymatic activity
Enzyme Commision number 2.1.1.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0008168 methyltransferase activity
GO:0034246 mitochondrial transcription factor activity
Biological Process
GO:0006390 mitochondrial transcription
GO:0006391 transcription initiation at mitochondrial promoter
GO:0032259 methylation
GO:0032786 positive regulation of DNA-templated transcription, elongation
Cellular Component
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
GO:0005759 mitochondrial matrix
GO:0034245 mitochondrial DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8c5u, PDBe:8c5u, PDBj:8c5u
PDBsum8c5u
PubMed37821701
UniProtP14908|MTF1_YEAST Mitochondrial transcription factor 1 (Gene Name=MTF1)

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