Structure of PDB 8c49 Chain B Binding Site BS02

Receptor Information

>8c49 Chain B (length=273) Species: 1291540 (Methanomethylophilus alvi) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VKYTDAQIQRLREYGNGTYEQKVFEDLASRDAAFSKEMSVASTDNEKKIK
GMIANPSRHGLTQLMNDIADALVAEGFIEVRTPIFISKDALARMTITEDK
PLFKQVFWIDEKRALRPMLAPNIFSVGRDLRDHTDGPVKIFEMGSCFRKE
SHSGMHLEEFTMLNLFDMGPRGDATEVLKNYISVVMKAAGLPDYDLVQEE
SDVFKETIDVEINGQEVCSAAVGPHYLDAAHDVHEPWSGAGFGLERLLTI
REKYSTVKKGGASISYLNGAKIN

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

8c49 Chain B Residue 310 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	8c49 Engineering mutually orthogonal PylRS/tRNA pairs for dual encoding of functional histidine analogues.
Resolution	1.82 Å
Binding residue (original residue number in PDB)	E218 S221
Binding residue (residue number reindexed from 1)	E216 S219
Annotation score	1

Enzymatic activity

Enzyme Commision number

6.1.1.26: pyrrolysine--tRNA(Pyl) ligase.

Gene Ontology

	Molecular Function
GO:0004812	aminoacyl-tRNA ligase activity
GO:0043767	pyrrolysyl-tRNA synthetase activity
GO:0046872	metal ion binding

View graph for
Molecular Function

External links

PDB	RCSB:8c49, PDBe:8c49, PDBj:8c49
PDBsum	8c49
PubMed	37051694
UniProt	M9SC49

[Back to BioLiP]