Structure of PDB 8ai6 Chain B Binding Site BS02

Receptor Information
>8ai6 Chain B (length=323) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LYFQGHMYNKTVSINLDSRCNASCDHCCFSSSPTSTTRMEKEYIRELVTE
FAKNKTIQVISFTGGEVFLDYKFLKELMEIIKPYEKQITLISNGFWGLSK
KKVQEYFHDMNSLNVIALTISYDEYHAPFVKSSSIKNILEHSRKYPDIDI
SLNMAVTKDKMSNHILEELGDSILGVKITKFPMISVGAAKTRIKQENIHK
FYSLEDEDSLHCPGYAIVYHHDGEIYPCCSPAIFETKITLREEYNQSFER
TVEKLNSNLLLFILRKEGFKWFLNILKENNKIEEFDIPYEFSSICGVCGS
LFNSAEKINYFYPYMEKYYNENF
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain8ai6 Chain B Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8ai6 Structural and mechanistic basis for RiPP epimerization by a radical SAM enzyme.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		C206 P207 C222 S224 I227 F263 C289 C292
Binding residue
(residue number reindexed from 1)		C212 P213 C228 S230 I233 F269 C295 C298
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding

View graph for
Molecular Function
External links
PDB RCSB:8ai6, PDBe:8ai6, PDBj:8ai6
PDBsum8ai6
PubMed38158457
UniProtQ45595|YYDG_BACSU Putative peptide biosynthesis protein YydG (Gene Name=yydG)

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