Structure of PDB 8act Chain B Binding Site BS02

Receptor Information
>8act Chain B (length=857) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIV
SREGGKVTAETEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVL
YNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPP
HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVILEDQ
IIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLE
KSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETT
VASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQE
QAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVYVTKGQNVQQVIYAT
GALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFE
QLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLI
EKPMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPE
AHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANY
AGFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMH
QLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKG
AEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQ
SRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLK
SAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQV
QAEQDNL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8act Chain B Residue 1003 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8act Cryo-EM structure of the folded-back state of human beta-cardiac myosin.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		T185 S242
Binding residue
(residue number reindexed from 1)		T183 S223
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:8act, PDBe:8act, PDBj:8act
PDBsum8act
PubMed37258552
UniProtP12883|MYH7_HUMAN Myosin-7 (Gene Name=MYH7)

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