Structure of PDB 8a4a Chain B Binding Site BS02

Receptor Information
>8a4a Chain B (length=172) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKN
EKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWS
TQIKTYSWDNAQVILVGNKCDMEDERVISTERGQHLGEQLGFEFFETSAK
DNINVKQTFERLVDIICDKMSE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8a4a Chain B Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8a4a Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector.
Resolution2.52 Å
Binding residue
(original residue number in PDB)		T44 T62
Binding residue
(residue number reindexed from 1)		T19 T37
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0031489 myosin V binding
Biological Process
GO:0006887 exocytosis
GO:0009306 protein secretion
GO:0015031 protein transport
Cellular Component
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0008021 synaptic vesicle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8a4a, PDBe:8a4a, PDBj:8a4a
PDBsum8a4a
PubMed35871249
UniProtP10949|RAB3C_BOVIN Ras-related protein Rab-3C (Gene Name=RAB3C)

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