Structure of PDB 7yun Chain B Binding Site BS02

Receptor Information
>7yun Chain B (length=92) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FQIEKWQIARCNKSKPQKFINDLMQVLYTNEYMATHSLTGAKSSTSRDKA
VKPAMNQNEVQEIIGVTKQLFPNTDDVSIRRMIGQKLNNCTK
Ligand information
Receptor-Ligand Complex Structure
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PDB7yun Structural insights into DNA recognition by the BEN domain of the transcription factor BANP.
Resolution2.13 Å
Binding residue
(original residue number in PDB)
Q190 N194 S217 Q258 N262
Binding residue
(residue number reindexed from 1)
Q17 N21 S44 Q85 N89
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003714 transcription corepressor activity
Biological Process
GO:0045666 positive regulation of neuron differentiation
GO:0045746 negative regulation of Notch signaling pathway

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Molecular Function

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Biological Process
External links
PDB RCSB:7yun, PDBe:7yun, PDBj:7yun
PDBsum7yun
PubMed37086783
UniProtQ5SZJ8|BEND6_HUMAN BEN domain-containing protein 6 (Gene Name=BEND6)

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