Structure of PDB 7y7p Chain B Binding Site BS02

Receptor Information
>7y7p Chain B (length=908) Species: 5141 (Neurospora crassa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VAARLRNIWPKFPKWLHEAPLAVAWEVTRLFMHCKVDLELKYDPSWSTAR
DVTDIWKTLYRLEKPPNDVFVTAMTGNFESKGSAVVLSAVLDYNPDNSPA
PLYLVKLKPLMFEQGCRLTRRFGPDRFFEILIPSPTSTSPSVPPVVSKQP
AVEEVIQWLTMGQHSLVGRQWRAFFAKDAGYRKPLRPIIKERVHFFAETG
ITFRPDEPVEQRTEFKVSQMLDWLLQLDNNTWQPHLKLFSRIQLGLSKTY
AIMTLEPHQIRHHKTDLLSPSGTGEVMNDGVGRMSRSVAKRIRDVLGLGD
VPSAVQGRFGSAKGMWVIDVDDTGDEDWIETYPSQRKWECDFVDKHQRTL
EVRSVASELKSAGLNLQLLPVLEDRARDKVKMRQAIGDRLINDLQRQFSE
QKHALNRPVEFRQWVYESYSSRATRVSHGRVPFLAGLPDSQEETLNFLMN
SGFDPKKQKYLQDIAWDLQKRKCDTLKSKLNIRVGRSAYIYMIADFWGVL
EENEVHVGFSSKFRDEEESFTLLSDCDVLVARSPAHFPSDIQRVRAVFKP
ELHSLKDVIIFSTKGDVPLAKKLSGGDYDGDMAWVCWDPEIVDGFVNAEM
PLEPDLSRYLKKDKTTFKQLMASHGTGSAAKEQTTYDMIQKSFHFALQPN
FLGMCTNYKERLCYINNSVSNKPAIILSSLVGNLVDQSKQGIVFNEASWA
QLRRELLGGALSLPDPMYKSDSWLGRGEPTHIIDYLKFSIARPAIDKELE
AFHNAEDGAHFWDPDLASYYTFFKEISDKSRSSALLFTTLKNRIGEVEKE
YGRPVRVNQVYEKWCAITPESKVIRLLELSFLADREMNTWALLRASTAFK
LYYHKSPKFVWQMAGRQLAYIKAQMTSRPGEGAPALMTAFMYAGLMPDKK
FTKQYVAR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7y7p Structural insights into the dual activities of the two-barrel RNA polymerase QDE-1.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
R591 R611 S677 Q736 R738 R783 D1011
Binding residue
(residue number reindexed from 1)
R182 R192 S247 Q306 R308 R353 D581
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003968 RNA-dependent RNA polymerase activity

View graph for
Molecular Function
External links
PDB RCSB:7y7p, PDBe:7y7p, PDBj:7y7p
PDBsum7y7p
PubMed36039765
UniProtQ9Y7G6

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