Structure of PDB 7xvu Chain B Binding Site BS02

Receptor Information

>7xvu Chain B (length=389) Species: 2116483 (Wuhan spiny eel influenza virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

EWRFPKSTCPGRSLQKMLQLNPHRHATAGSQAATIPNREPFISCSQDECR
LFTLDHDVSTPGAYDGITWEDRSKRRRLVSFPLGSELTLDNMKVHLSGWS
GTACHDGKEWTYATVNGPDNSAVMRLKYGDQIRGSFPSYANNILRTQESE
CVCIDGKCYIIVIDGPAGGTATPKVLVTREGEVTSEIIVTGRNKMGEECS
CLATNRTWIECLCRDNAFSAKRPIIRIDTVAGTARGYLMCSDTYLDTPRP
ADGSITGSCETDGTSGGGGVKGAFALSRTTEATTERFYVRTVSSSARSGA
VFYKTTDDPTESNNPLTLIGTAVGGAIPMWYSFSFEIPGKVCDQTCIGLE
MGLTMGHQLWTSNSVAVYCVIGDNLDWDSTTDVVPADIV

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

7xvu Chain B Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7xvu Structure of neuraminidase from influenza B-like viruses derived from spiny eel
Resolution	1.6 Å
Binding residue (original residue number in PDB)	D298 S302 D329 G349 G351
Binding residue (residue number reindexed from 1)	D215 S219 D246 G266 G268
Annotation score	4

Enzymatic activity

Enzyme Commision number

3.2.1.18: exo-alpha-sialidase.

Gene Ontology

	Molecular Function
GO:0004308	exo-alpha-sialidase activity

	Biological Process
GO:0005975	carbohydrate metabolic process

	Cellular Component
GO:0016020	membrane
GO:0033644	host cell membrane
GO:0055036	virion membrane

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Molecular Function

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Cellular Component

External links

PDB	RCSB:7xvu, PDBe:7xvu, PDBj:7xvu
PDBsum	7xvu
PubMed	36191180
UniProt	A0A2P1GNP4

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