Structure of PDB 7x5e Chain B Binding Site BS02

Receptor Information
>7x5e Chain B (length=106) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HLTRDELRAKALHIPFPVEKIINLPVVDFNEMMSKEQFNEAQLALIRDIR
RRGKNKVAAQNCRKRKLENIVELEQDLDHLKDEKEKLLKEKGENDKSLHL
LKKQLS
Ligand information
Receptor-Ligand Complex Structure
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PDB7x5e Structural basis of transcription regulation by CNC family transcription factor, Nrf2.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		R499 R502 K506 A510 R517 K518
Binding residue
(residue number reindexed from 1)		R47 R50 K54 A58 R65 K66
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:7x5e, PDBe:7x5e, PDBj:7x5e
PDBsum7x5e
PubMed36454022
UniProtQ16236|NF2L2_HUMAN Nuclear factor erythroid 2-related factor 2 (Gene Name=NFE2L2)

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