Structure of PDB 7wrg Chain B Binding Site BS02

Receptor Information
>7wrg Chain B (length=783) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DSIIVAVRVRPFNDREKTRNCKLVIEMPDEETTVIRDPKTNDEKTYDHSY
WSHDGFSEKKNGYLEPTDPHYADQRRVFEDLGRGVLANAWAGYNCSLFAY
GQTGSGKSYSIVGFKNNKGIVPIVCEELFKQIADNKKKNMQFEVFVSMME
IYCEKVRDLLSSTPPPKGGLKVREHPKNGFYVENLTTVPVNSFKEIEAKI
EEGTKSRTIAATQMNATSSRAHTIVKITFNQKSGTSMKKSEINLVDLAGS
EGDRLKEGIVINQSLTTLGRVIKALHDSIPYRDSVLTCLLKNALGGNSKT
IMIAAISPADINFEETLSTLRFADRAKSIKTNAVVNENQTERALRELREE
NLRLQSQIQGGTAGNEEIEKLRRQLAENQKEMEEMEKSWQQKIAEEAAKA
SEKVEMEAKKKKMCHLWNLNEDPALTNVIVHFIPVGESVVGNKNFIQMSG
LSILPQHVTLKNDGNNQIHLSPCSEDLDIFINGKPVHGETQLQQNDRVFF
GGNHLYVFNNPTKKGIRTDITYENAQAEIAQNHAAALRDLILEEELMSTL
PLVQRANAMATELGRNVKFEIVLVSPEMRGLTSGLTEIWVKVHNISEDTY
FLWEKSRFMNRYYGMQEMYEAKQDGSEKERDPFYEPPDSPVFIASSVVFL
QSLAYLIDVEEQFPIVDLSGQEIGLLTVGLSPCSTTGKELRGEYVEDPDQ
LIGKNIAFKVKVISAVGLPRRILKSNCKYRFFGSKKMTTTATVSGNTPAY
GHEETFQFKPVTKEVADYLANSNLYITFWGTQR
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7wrg Chain B Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7wrg The architecture of kinesin-3 KLP-6 reveals a multilevel-lockdown mechanism for autoinhibition.
Resolution3.16 Å
Binding residue
(original residue number in PDB)		K113 S114
Binding residue
(residue number reindexed from 1)		K107 S108
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003774 cytoskeletal motor activity
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0007018 microtubule-based movement
GO:0030705 cytoskeleton-dependent intracellular transport
Cellular Component
GO:0005871 kinesin complex
GO:0005874 microtubule
GO:0030424 axon
GO:0030425 dendrite
GO:0031966 mitochondrial membrane
GO:0043025 neuronal cell body
GO:0097730 non-motile cilium

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7wrg, PDBe:7wrg, PDBj:7wrg
PDBsum7wrg
PubMed35879313
UniProtG5EFQ4

[Back to BioLiP]