Structure of PDB 7v5i Chain B Binding Site BS02

Receptor Information
>7v5i Chain B (length=400) Species: 1219065 (Vibrio proteolyticus NBRC 13287) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NIMSSAFYQQIQQQIEEVKAEGLYKSERIITSQQQAAVKIASGEEVLNFC
ANNYLGLANHPALIEAGKAGMDEHGFGMASVRFICGTQDIHKELEQKLST
FLGKEDTILYTSCFDANAGLFETILDKEDAIISDALNHASIIDGVRLCKA
MRFRYSNNNMTELEEQLIAAKDAGARNILIVTDGVFSMDGVVANLPAICD
LAEKYGALTMVDDSHAVGFMGKTGAGTHEYHDVVDRIDIITGTLGKAMGG
ASGGYTSGKKEVIEWLRQRSRPYLFSNSVAPAIVSASIRVLDLLQESGDL
RDRLWENATHFRTRMSEAGFTLAGADHAIIPIMLGDAKVAAEFAERALEK
GIYVIGFSFPVVPKGQARIRTQMSAAHSREQLDKAIDAFIEVGRDMEIIK
Ligand information
Ligand IDPLP
InChIInChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)
InChIKeyNGVDGCNFYWLIFO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341Cc1ncc(CO[P](O)(O)=O)c(C=O)c1O
OpenEye OEToolkits 1.5.0Cc1c(c(c(cn1)COP(=O)(O)O)C=O)O
ACDLabs 10.04O=P(O)(O)OCc1cnc(c(O)c1C=O)C
FormulaC8 H10 N O6 P
NamePYRIDOXAL-5'-PHOSPHATE;
VITAMIN B6 Phosphate
ChEMBLCHEMBL82202
DrugBankDB00114
ZINCZINC000001532514
PDB chain7v5i Chain B Residue 500 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7v5i Structural insights into the substrate selectivity of alpha-oxoamine synthases from marine Vibrio sp. QWI-06.
Resolution3.08 Å
Binding residue
(original residue number in PDB)		S112 C113 H138 D212 S214 H215 T243 K246
Binding residue
(residue number reindexed from 1)		S112 C113 H138 D212 S214 H215 T243 K246
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.1.29: glycine C-acetyltransferase.
Gene Ontology
Molecular Function
GO:0008890 glycine C-acetyltransferase activity
GO:0016740 transferase activity
GO:0016746 acyltransferase activity
GO:0016874 ligase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006567 threonine catabolic process
GO:0009058 biosynthetic process
GO:0019518 L-threonine catabolic process to glycine
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7v5i, PDBe:7v5i, PDBj:7v5i
PDBsum7v5i
PubMed34838420
UniProtU3BPN5

[Back to BioLiP]