Structure of PDB 7sj2 Chain B Binding Site BS02

Receptor Information
>7sj2 Chain B (length=439) Species: 7955,44689 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLFDSYRDNVAGKSFQTRLCLPMPIDVVYTWVNGTDPKLIKEVTELKRSN
TASRFEDNEELRYSLRSIEKHAPWVRHIFIVTNGQIPSWLNLDNPRVSVV
THQDIFQNQTHLPTFSSPAIETHIHRIPGLSQKFIYLNDDVMFGKDVWPD
DFYSHSKGQKVYLTWPADSLRYVNRLLNAQFGFTSRKVPAHMPHMIDRLI
MQELQDTFPQEFDKTSSHRVRHSEDMQFAFSYFYFLMSAVQQLNISEVFD
EIDTDHSGVLSDREIRTLATRIHELPLSLQDLTSLEQMLINCSKSLPSNL
THSPTQEAYYDPSMPPVTKGLVIHCKPITERIHKAFKDQNKYKFEIMGEE
EIAFKMIRTNVSHVVGQLDDIRKNPRKFICLNDNIDHIHKDAGTVKAVLR
DFYESMFPLPSQFELPREYRNRFLHMTELQEWRIYRDKL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7sj2 Chain B Residue 604 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7sj2 Structures of the mannose-6-phosphate pathway enzyme, GlcNAc-1-phosphotransferase.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		D219 N471
Binding residue
(residue number reindexed from 1)		D140 N382
Annotation score1
Enzymatic activity
Enzyme Commision number ?
2.7.8.17: UDP-N-acetylglucosamine--lysosomal-enzyme N-acetylglucosaminephosphotransferase.
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0016772 transferase activity, transferring phosphorus-containing groups

View graph for
Molecular Function
External links
PDB RCSB:7sj2, PDBe:7sj2, PDBj:7sj2
PDBsum7sj2
PubMed35939698
UniProtQ54MP1;
Q5RGJ8

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