Structure of PDB 7rtm Chain B Binding Site BS02

Receptor Information
>7rtm Chain B (length=571) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LFGGLVLDVKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLL
GEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFK
FCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASL
ICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCALPENPNNHTLQ
YWKEHSIPTADVNWANLTVSECQEMHGEFIGSACGHHGPYTPDVLFWSCI
LFFATFIVSSTLKTFKTSRYFPTRVRSTVSDFAVFLTIFTMVILDFLIGV
PSPKLQVPSVFKPTRDDRGWFISPIGPNPWWTVIAAIIPALLCTILIFMD
QQITAVIINRKEHKLKKGCGYHLDLLVVAIMLGVCSLMGLPWFVAATVLS
ITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAVLK
FIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLR
KVHLFTLVQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRE
LSWLDDLMPESKKKKLDDAKK
Ligand information
Ligand IDCO3
InChIInChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
InChIKeyBVKZGUZCCUSVTD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(=O)([O-])[O-]
ACDLabs 10.04
CACTVS 3.341		[O-]C([O-])=O
FormulaC O3
NameCARBONATE ION
ChEMBL
DrugBankDB14531
ZINC
PDB chain7rtm Chain B Residue 1103 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7rtm Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		S537 T538 I601
Binding residue
(residue number reindexed from 1)		S87 T88 I151
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005452 solute:inorganic anion antiporter activity
Biological Process
GO:0006820 monoatomic anion transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7rtm, PDBe:7rtm, PDBj:7rtm
PDBsum7rtm
PubMed34584093
UniProtQ6RVG2|S4A8_RAT Electroneutral sodium bicarbonate exchanger 1 (Gene Name=Slc4a8)

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